Liu, Yung-Chuan
Home Faculty & Staff Faculty
Yung-Chuan Liu , Professor
Tel:886-4-22853769;886-4-2284-0510 ext 607
E-mail: ycliu@nchu.edu.tw
BS, National Cheng Kung University, Taiwan (1977-1981)
MS, National Tsing Hua University, Taiwan (1981-1983)
PhD, National Tsing Hua University, Taiwan (1990-1995)
Research Scientist, Union Chem. Lab, ITRI (1988-1996)
Associate Professor, National Chung Hsing University
(1996-2003)
Professor, National Chung Hsing University (2003-)

 

Research Interests
In Bioengineering aspect
Bioprocess Development and Optimization
Bioreactor Design
Metabolic Engineering
In Bioassay aspect
Development and application of immunochromatographic test.
Development of electrochemical immunoassay.
Development of microchip for bioassay.
 
Teaching subject
Publications
  1. Chung, C.-F., Lin, S.-C., Juang, T.-Y., and Liu, Y.-C.*, “Shaking rate during production affects the activity of Escherichia coli surface-displayed Candida antarctica lipase A”, Catalysts, 10, 382 (2020) (SCI)
  2. Fang, Y.-T., Li, S.-Y., Hu, N.-J., Yang, J., Liu, J.-H., and Liu, Y.-C.*, “Study on cecropin B2 production via construct bearing intein oligopeptide cleavage variants”, Molecules, 25,1005 (2020) (SCI)
  3. Hsu, Y.-C., Chang, P.-H., Lin, C.-N., Li, C.-Y., Juang, T.-Y. and, Liu, Y.-C.* “A fermentation process for the in situ intercalation of surfactin into layered double hydroxides”, Appl. Clay Sci., 182, 105247 (2019) (SCI)
  4. Chang, P.-H., Li, S.-Y., Juang, T.-Y. and, Liu, Y.-C.*, “Mg-Fe layered double hydroxides enhance surfactin production in bacterial cells”, Crystals, 9, 355 (2019) (SCI)
  5. Fang, Y.-T., Lai, W.-S., Liu, J.-H. and, Liu, Y.-C.*, “Enhanced cecropin B2 production via chitin binding domain and intein self-cleavage system”, Biotechnol. Appl. Biochem., 66, 209-215 (2019) (SCI)
  6. Wang, C.-C., Wu, J.-Y., Chang, C.-Y., Yu, S.-T. and, Liu, Y.-C.*, “Enhanced exopolysaccharide production by Cordyceps militaris using repeated batch cultivation”, J. Biosci. Bioeng., 127, 499-505 (2019) (SCI)
  7. Liu, Y.-C.* and Chen, C.-C., “Enhanced high-molecular-weight exopolysaccharides production via Tuber borchii cultivation”, New Biotechnol., 44, S131 (2018) (SCI)
  8. Wu, J.-Y., Liao, J.-H., Shieh, C.-J., Hsieh, F.-C. and, Liu, Y.-C.*, “Kinetic analysis on precursors for iturin A production from Bacillus amyloliquefaciens BPD1”, J. Biosci. Bioeng., 126, 630-635 (2018) (SCI)
  9. Peng, Y.-H., Chou, Y.-J., Liu, Y.-C., Jen, J.-F., Chung, K.-R. and Huang, J.-W., “Inhibition of cucumber Pythium damping-off pathogen with zoosporicidal biosurfactants produced by Bacillus mycoides”, J. Plant Dis. Prot., 124, 481–491 (2017) (SCI)
  10. Huang, S.-M., Hung, T.-H., Liu, Y.-C., Kuo, C.-H. and Shieh, C.-J., “Green synthesis of ultraviolet absorber 2-ethylhexyl salicylate: Experimental design and artificial neural network modeling”, Catalysts, 7, 342 (2017) (SCI)
  11. Huang, S.-M., Li, H.-J., Liu, Y.-C., Kuo, C.-H. and Shieh, C.-J., “An efficient approach for lipase-catalyzed synthesis of retinyl laurate nutraceutical by combining ultrasound assistance and Artificial Neural Network optimization”, Molecules, 22,1972 (2017) (SCI)
  12. Kan, S.-C., Lee, C.-C., Hsu, Y.-C., Peng, Y.-H., Chen, C.-C., Huang, J.-J., Huang, J.-W., Shieh, C.-J., Juang, T.-Y., and Liu, Y.-C.*, “Enhanced surfactin production via the addition of layered double hydroxides”, J. Taiwan Inst. Chem. Engrs., 80, 10-15 (2017) (SCI, 4.2, Chem. Eng., 16/136=0.118)
  13. Lin, J.-H., Lee, M.-C., Sue, Y.-S., Liu, Y.-C. and Li, S.-Y., “Cloning of phaCAB genes from thermophilic Caldimonas manganoxidans in Escherichia coli for poly(3-hydroxybutyrate) (PHB) production”, Appl. Microbiol. Biotechnol., 101, 6419-6430 (2017) (SCI, 3.4, Biotechnol. & Appl. Microbiol., 44/160=0.275)
  14. Huang, S.-M., Kuo, C.-H., Chen, C.-A., Liu, Y.-C.*, Shieh, C.-J., “RSM and ANN modeling-based optimization approach for the development of ultrasound-assisted liposome encapsulation of piceid”, Ultrason. Sonochem., 36, 112-122 (2017) (SCI, 4.218, Acoustics, 2/31=0.06)
  15. Lin, C.-C., Yap, C. J. S., Kan, S.-C., Hsueh, N.-C., Yang, L.-Y., Shieh, C.-J., Huang, C.-C. and Liu, Y.-C.*, “Deciphering characteristics of the designer cellulosome from Bacillus subtilis WB800N via enzymatic analysis”, Biochem. Eng. J., 117,147-155 (2017) (SCI, 2.892, Chem. Eng., 32/136=0.235)
  16. Liao, J.-H., Chen, P.-Y., Yang, Y.-L., Kan, S.-C., Hsieh, F.-C. and Liu, Y.-C.*, “Clarification of the antagonistic effect of the lipopeptides produced by Bacillus amyloliquefaciens BPD1 against Pyricularia oryzae via in situ MALDI-TOF IMS analysis”, Molecules, 21, 1670 (2016) (SCI, 2.416, Chem. Org., 22/58=0.379)
  17. Kuo, C.-H., Lin, J.-A., Chien, C.-M. J., Tsai, C.-H., Liu, Y.-C.*, Shieh, C.-J., “Formation of amide bond catalyzed by lipase in aqueous phase for peptide synthesis”, J. Mol. Cata. B: Enzym., 129, 15-20 (2016) (SCI, 2.189, Chem., Phys, 76/144=0.53)
  18. Liu, Y.-C., Lee, Y.-C., Yu, W.-C., Lin, C,-C., Yap, C. J. S., “Study on cultivation of Bacillus subtilis WB800N for production of recombinant cellulosome”, New Biotechnol., 33S, S102 (2016) (SCI, 1.842, Biotechnol. Appl. Microbiol., 82/160=0.51)
  19. Shieh, C.-J., Lin, J.-A. and Liu, Y.-C., “Synthesis of lipase-catalyzed retinol ester derivative”, New Biotechnol., 33S, S102 (2016) (SCI, 1.842, Biotechnol. Appl. Microbiol., 82/160=0.51)
  20. Lin, J.-A., Kuo, C.-H., Chen, B.-Y., Li, Y., Liu, Y.-C., Chen, J.-H., Shieh, C.-J., “A novel enzyme-assisted ultrasonic approach for highly efficient extraction of resveratrol from Polygonum cuspidatum”, Ultrason. Sonochem., 32, 258-264 (2016) (SCI, 4.556, Acoustics, 1/32=0.03)
  21. Yeh, C.-W., Kan, S.-C., Lin, C.-C., Shieh, C.-J., Liu, Y.-C.*, “Polyhydroxylated steroids and triterpenoids from an entophytic fungus, Hypocreales sp. NCHU01 isolated from T. magnatum”, J. Taiwan Inst. Chem. Engrs., 55, 1-6 (2016) (SCI, 3.0 Chem. Eng., 19/134=0.14)
  22. Kho, C.-H., Cheng, H.-Y., Kan, S.-C., Lin, C.-C., Chiou, P.-C., Chang, C.-Y., Shieh, C.-J. and Liu, Y.-C.*, “Analysis of exopolysaccharide production patterns of Cordyceps militaris under various light-emitting diodes”, Biochem. Eng. J., 112, 226-232 (2016) (SCI, 2.692, Chem. Eng. , 16/135=0.12)
  23. Kuo, C.-H., Chen, B.-Y., Liu, Y.-C., Chen, J.-H. and Shieh, C.-J. “Production of resveratrol from piceid deglycosylation using cellulase”, Catalysts, 6, 32 (2016) (SCI, 2.000, Chem. Phys., 77/139=0.554)
  24. Lai, W.-S., Kan, S.-C., Lin, C.-C., Shieh, C.-J. and Liu, Y.-C.*, “Antibacterial peptide cecropinB2 production via various host and construct systems”, Molecules, 21, 103 (2016) (SCI, 2.416, Chem. Org., 22/58=0.379)
  25. Kan, S.-C., Zang, C.-Z., Yeh, C.-W., Chang, W.-F., Lin, C.-C., Shieh, C.-J. and Liu, Y.-C.*, “Enhanced bioconversion rate and released substrate inhibition in (R)-phenylephrine whole-cell bioconversion via partial acetone treatment”, Enzyme Microb. Tech., 86, 34-38 (2016) (SCI, 2.322, Biotech. Microbiol., 74/163=0.454)
  26. Zang, C.-Z., Kan, S.-C., Yeh, C.-W., Lin, C.-C., Shieh, C.-J. and Liu, Y.-C.*, “Ultrasound-assisted (R)-phenylephrine whole-cell bioconversion by S. marcescens N10612”, Ultrason. Sonochem., 26, 415-421 (2015) (SCI, 4.556, Acoustics, 1/32=0.03)
  27. Kan, S.-C., Chen, C.-M., Lin, C.-C., Wu, J.-Y., Shieh, C.-J., Liu, Y.-C.*, “Deciphering EGFP production via surface display and self-cleavage intein system in different hosts”, J. Taiwan Inst. Chem. Engrs., 55, 1-6 (2015) (SCI, 3.0 Chem. Eng., 19/134=0.14)
  28. Dauner, A. L., Mitra, I., Gilliland Jr., T., Seales, S., Pal, S., Yang, S.-C., Guevara, C., Chen, J.-H., Liu, Y.-C., Kochel, T. J., Wu, S.-J. L., “Development of a pan-serotype reverse transcription loop-mediated isothermal amplification assay for the detection of dengue virus”, Diagn. Microbiol. Infect. Dis., 83, 30-36 (2015) (SCI, 2.457, Microbiol. , 66/119=0.55)
  29. Kan, S.-C., Chang, W.-F., Lan, M.-C., Lin, C.-C., Lai, W.-S., Shieh, C.-J., Hsiung, K.-P. and Liu, Y.-C.*, “Development of an enzymatic chromatography strip with NADH-tetrazolium coupling reactions for quantitative L-lactate analysis”, Anal. Biochem., 471, 61-66 (2015) (SCI, 2.219, Anal. Chem., 32/74=0.43)
  30. Lee, C.-C., Chen, Y.-T., Chiu, C.-C., Liao, W.-T., Liu, Y.-C. and Wang, H.-M. D., “Polygonum cuspidatum extracts as bioactive antioxidaion, anti-tyrosinase, immune stimulation and anticancer agents” J. Biosci. Bioeng., 119,464-469 (2015) (SCI, 1.737, Food Sci. Technol., 48/124=0.39)
  31. Chang, W.-F., Huang, S.-Y., Lee, R.-H. and Liu, Y.-C.*, “Construction of a thin-film immunosensor with self-doping polyaniline modified electrode for human serum albumin detection” J. Polym. Res., 21, 573-579 (2014) (SCI, 1.897, Polym. Sci., 34/82=0.41)
  32. Zang, C.-Z., Yeh, C.-W., Chang, W.-F., Lin, C.-C., Kan, S.-C., Shieh, C.-J. and Liu, Y.-C.*, “Identification and enhanced production of prodigiosin isoform pigment from Serratia marcescens N10612” J. Taiwan Inst. Chem. Engrs., 45, 1133-1139 (2014) (SCI, 3.0 Chem. Eng., 19/134=0.14)
  33. Kuo, C.-H., Chen, G.-J., Chen, C.-I, Liu, Y.-C.* and Shieh, C.-J., “Kinetics and optimization of lipase-catalyzed synthesis of rose fragrance 2-phenylethyl acetate through transesterification”, Proc. Biochem., 49, 437-444 (2014) (SCI, 2.414, Chem. Eng., 25/133=0.188)
  34. Yeh, C.-W., Zang, C.-Z., Lin, C.-C., Kan, S.-C., Chang, W.-F., Shieh, C.-J. and Liu, Y.-C.*, “Quantitative and morphologic analysis on exopolysaccharide and biomass production from a truffle endophytic fungus Hypocreales sp. NCHU01”, J. Taiwan Inst. Chem. Engrs., 45, 108-113 (2014) (SCI, 3.0 Chem. Eng., 19/134=0.14)
  35. Kuo, C.-H., Chen, B.-Y., Liu, Y.-C., Chang, C.-M. J., Deng, T.-S., Chen, J.-H. and Shieh, C.-J., “Optimized ultrasonic-assisted extraction of phenolic compounds from Polygonum cuspidatum”, Molecules, 19, 67-77 (2014) (SCI, 2.428, Chem. Org., 24/57=0.42).
  36. Lin,C.-C., Liu, T.-T., Kan, S.-C., Zang, C.-Z., Yeh, C.-W., Wu, J.-Y., Chen, J.-H., Shieh, C.-J. and Liu, Y.-C.*, “Production of D-Hydantoinase via surface display and self-cleavage system”, J. Biosci. Bioeng., 116, 562-566 (2013) (SCI, 1.737, Food Sci. Technol., 48/124=0.39)
  37. Wu, J.-Y., Chen, H.-B., Chen, M.-J., Kan, S.-C., Shieh, C.-J. and Liu, Y.-C.*, “Quantitative analysis of LED effects on edible mushroom Pleurotus erygii in solid and submerged cultures”, J. Chem. Technol. Biotechnol., 88, 1841-1846 (2013) (SCI, 2.504, Chem. Eng., 23/133=0.17).
  38. Ko, Y.-M., Chen, C.-I, Lin, C.-C., Kan, S.-C., Zang, C.-Z., Yeh, C.-W., Chang, W.-F., Shieh, C.-J. and Liu, Y.-C.*, “Enhanced D-hydantoinase activity performance via immobilized cobalt ion affinity membrane and its kinetic study”, Biochem. Eng. J., 79, 200-205 (2013) (SCI, 2.579, Chem. Eng. , 21/133=0.158)
  39. Kuo, C.-H., Peng L.-T., Kan S.-C. Liu, Y.-C.* and Shieh, C.-J., “Lipase-immobilized biocatalytic membranes for biodiesel production”, Bioresour. Technol., 145, 229-232 (2013) (SCI, 4.98, Energy & Fuels, 8/81=0.098).
  40. Lin, C.-C., Wei, C.-H., Chen, C.-I, Shieh, C.-J. and Liu, Y.-C.*, “Characteristics of the photosynthesis microbial fuel cell with a chlorophyll biofilm”, Bioresour. Technol., 135,640-643 (2013) (SCI, 4.98, Energy & Fuels, 8/81=0.098)
  41. Chen, H.-B., Chen, C.-I, Chen, M.-J., Lin, C.-C., Kan, S.-C., Zang, C.-Z., Yeh, C.-W., Shieh, C.-J. and Liu, Y.-C.*, “The use of mushroom hydrolysate from waste bag-log as the nitrogen source to mycelium biomass and exopolysaccharide production in Pleurotus eryngii cultivation”, J. Taiwan Inst. Chem. Engrs., 44, 163-168 (2013) (SCI, 3.0 Chem. Eng., 19/134=0.14)
  42. Kuo, C.-H., Huang, W.-H., Lee, C.-K., Liu, Y.-C., Chang, C.-M. J., Yang, H. and Shieh, C.-J., “Biofuel cells composed by using glu­cose oxi­dase on chitosan coated car­bon fiber cloth”, 8, 9242-9255 (2013), Int. J. Electrochem. Sci. (SCI, 3.73, Electrochem., 9/27=0.33)
  43. Kuo, C.-H., Hsiao, F.-W., Chen, J.-H., Hsieh, C.-W., Liu, Y.-C. and Shieh, C.-J., “Kinetic aspects of ultrasound-accelerated lipase catalyzed acetylation and optimal synthesis of 4'-acetoxyresveratrol”, Ultrason. Sonochem., 20, 546-552 (2013) (SCI, 3.687, Acoustics, 1/30=0.03)
  44. Chen, B.-Y., Kuo, C.-H., Liu, Y.-C., Ye, L., Chen, J.-H. and Shieh, C.-J., “Ultrasonic-assisted extraction of the botanical dietary supplement resveratrol and other constituents of polygonum cuspidatum”, J. Nat. Prod., 75, 1810-1813 (2012) (SCI, 3.13, Plant Sci., 27/190=0.142)
  45. Wu, J.-Y., Chen, C.-I, Chen, C.-M., Lin, C.-C., Kan, S.-C. Shieh, C.-J. and Liu, Y.-C.*, “Cell disruption enhanced the pure EGFP recovery from an EGFP-intein- surface protein production system in recombinant E. coli”, Biochem. Eng. J., 68, 12-18 (2012) (SCI, 2.692, Chem. Eng. , 16/135=0.12)
  46. Kuo, C.-H., Chen, H.-H., Chen, J.-H., Liu, Y.-C. and Shieh, C.-J., “High yield of wax ester synthesized from cetyl alcohol and octanoic acid by Lipozyme RMIM and Novozym 435”, Int. J. Mol. Sci., 13, 11694-11704 (2012) (SCI, 2.464, Chem. Multi., 48/152=0.316).
  47. Kuo, C.-H., Chen, G.-J., Twu, Y.-K., Liu, Y.-C.*, and Shieh, C.-J., “Optimum lipase immobilized on diamine-grafted PVDF membrane and its characterization”, Ind. Eng. Chem. Res., 51, 5141-5147 (2012) (SCI, 2.206, Chem. Eng. , 30/133=0.226).
  48. Kuo, C.-H., Liu, Y.-C., Chang, C.-M.-J., Chen, J.-H., Chang, C., and Shieh, C.-J., “Optimum conditions for lipase immobilization on chitosan-coated Fe3O4 nanoparticles”, Carbohyd. Polym., 87, 11694-11704 (2012) (SCI, 3.463, Anal. Chem., 3/70=0.05)
  49. Chen, C.-I, Ko, Y.-M., Shieh, C.-J. and Liu, Y.-C.*, “Development of the reversible PGA immobilization by using the immobilized metal ion affinity membrane”, J. Memb. Sci., 401-402, 33-39 (2012) (SCI, 3.673, Chem. Eng. , 8/135=0.06)
  50. Chen, H.-C., Kuo, C.-H., Chen. H.-H., Liu, Y.-C. and Shieh, C.-J., “Optimization of enzymatic synthesis of cetyl 2-ethylhexanoate by Novozym® 435”, J. Am. Oil Chem. Soc., 88:1917–1923 (2012) (SCI, 1.587, Food Sci. Technol., 43/128=0.34 )
  51. Kuo, C.-H., Hsiao, F.-W., Dai, S.-M., Chang, C.-M. J., Lee, C.-C., Shieh, C.-J. and Liu, Y.-C.*, “Lipase catalyzed acetylation of 3,5,4′-trihydroxystilbene: optimization and kinetics study”, Bioproc. Biosyst. Eng., 35, 1137-1145 (2012) (SCI, 2.060, Chem. Eng., 31/135=0.23)
  52. Chen, H.-C., Kuo, C.-H., Tsai, W.-C., Chung, Y.-L., Chiang, W.-D., Chang, C.-M.-J., Liu, Y.-C. and Shieh, C.-J., “Product Selectivity and optimization of lipase-catalyzed 1,3-propylene glycerol esters by mixture design and RSM”, J. Am. Oil Chem. Soc., 89, 231-241 (2012) (SCI, 1.587, Food Sci. Technol., 43/128=0.34 )
  53. Lee, C.-C., Chen, H.-C., Ju, H.-Y., Chen, J.-H., Kuo, C.-H., Chung, Y.-L., Liu, Y.-C. and Shieh, C.-J., “Green and efficient production of octyl hydroxyphenylpropionate using an ultrasound-assisted packed-bed bioreactor”, J. Ind. Microbiol. Biotechnol., 39, 655-660 (2012) (SCI, Biotechnol. & Appl. Microbiol., 63/160=0.40)
  54. Hu, S.-H., Kuo, C.-H., Chang, C.-M.-J., Liu, Y.-C., Chiang, W,-D., Shieh, C.-J., “Solvent selection and optimization of a-chymotrypsin-catalyzed synthesis of N-Ac-Phe-Tyr-NH2 using mixture design and response surface methodology”, Biotechnol. Prog., 28, 1443-1449 (2012) (SCI, 2.178, Food Sci. Technol., 26/128=0.20)
  55. Kuo, C.-H., Chiang, S.-H., Ju, H.-Y., Chen, Y.-M., Liao, M.-Y., Liu, Y.-C. and Shieh, C.-J., “Enzymatic Synthesis of Rose Aromatic Ester (2-Phenylethyl Acetate) by Lipase”, J. Sci. Food Agri., 92, 2141-2147 (2012) (SCI, 1.360, Agriculture, 9/55=0.16)
  56. Kuo, C.-H., Ju, H.-Y., Chu, S.-W., Chen, J.-H., Chang, C.-M. J., Liu, Y.-C.* and Shieh, C.-J., “Optimization of lipase-catalyzed synthesis of cetyl octanoate in supercritical carbon dioxide”, J. Am. Oil Chem. Soc., 89, 103-110 (2012) (SCI, 1.587, Food Sci. Technol., 43/128=0.34 )
  57. Ju, H.-Y., Kuo, C.-H., Too, J.-R., Huang, H.-Y., Twu, Y.-K., Chang, C.-M. J., Liu, Y.-C., Shieh, C.-J., “Optimal covalent immobilization of α-chymotrypsin on Fe3O4-chitosan nanoparticles”, J. Mol. Cata. B: Enzym 78, 9-15 (2012) (SCI)
  58. Ko, Y.-M., Chen, C.-I, Shieh, C.-J. and Liu, Y.-C.*, “Simultaneous purification and immobilization of D-hydantoinase on the immobilized metal affinity membrane via coordination bonds”, Biochem. Eng. J., 61, 20-27 (2012) (SCI, 2.692, Chem. Eng. , 16/135=0.12)
  59. Ju, H.-Y., Kuo, C.-H., Too, J.-R., Liu, Y.-C. and Shieh, C.-J., “A green peptide synthesis-using a magnetic biocatalyst in a stirred-tank bioreactor”, Biocatal. Agr. Biotechol., 1, 20–24 (2012)(SCI).
  60. Chen, G.-J., Kuo, C.-H., Yu, C.-C., Shieh, C.-J. and Liu, Y.-C.*, “Effect of membranes with various hydrophobic/hydrophilic properties on lipase immobilized activity and stability”, J. Biosci. Bioeng., 113, 167-172 (2012) (SCI, 1.707, Food Sci. Technol., 38/128=0.30)
  61. Chen, C.-I, Ko, Y.-M., Shieh, C.-J. and Liu, Y.-C.*, “Direct penicillin G acylase immobilization by using the self-prepared immobilized metal affinity membrane”, J. Memb. Sci., 380, 34-40 (2011) (SCI, 3.673, Chem. Eng. , 8/135=0.06)
  62. Wu, J.-Y., Tsai, T.-Y., Liu, T.-T., Lin, C.-C., Chen, J.-H., Yang, S.-C., Shieh, C.-J. and Liu, Y.-C.*, “Production of recombinant EGFP via surface display of ice nucleation protein and self-cleavage intein”, Biochem. Eng. J., 54, 158-163 (2011) (SCI, 2.692, Chem. Eng. , 16/135=0.12)
  63. Zang, C.-Z., Chang, Y.-N., Chen, H.-B., Wu, J.-Y., Chen, C.-I, Huang, J.-W., Shih, H.-D. and Liu, Y.-C.*, “Deciphering the roles of fatty acids and oils in fungichromin enhancement from Streptomyces padanus”, J. Taiwan Inst. Chem. Engrs., 42, 413-418 (2011) (SCI, 1.488, Chem. Eng., 47/135=0.35)
  64. Chang, W.-F., Wang, S.-J., Lai, S.-F., Shieh, C.-J., Hsiung, K.-P. and Liu, Y.-C.*, “Evaluation on the use of reactive dyes modified polylysine as the biomarker in ICT application”, Anal. Biochem., 311, 236-240 (2011) (SCI, 3.236, Anal. Chem., 16/73=0.22)
  65. Chen, H.-C., Ju, H.-Y., Wu, T.-T., Liu, Y.-C., Lee, C.-C., Chang, C., Chung, Y.-L. and Shieh, C.-J., “Continuous production of lipase-catalyzed biodiesel in a packed-bed reactor: optimization and enzyme reuse study”, J. Biomed. Biotechnol., ID 950725 (2011) (SCI, 1.230, Biotechnol. & Appl. Microbiol., 111/160=0.70 )
  66. Ko, Y.-M., Chen, C.-I, Chang, H.-C., Chen, H.-M., Shieh, C.-J., Syu, Y.-J. and Liu, Y.-C.*, “Exploring the complex effects of metal ions on D-hydantoinase purification with an immobilized metal affinity membrane”, J. Chin. Inst. Chem. Engrs., 42, 735-740 (2011) (SCI, 1.488, Chem. Eng., 47/135=0.35)
  67. Chen, H.-C., Kuo, C.-H., Twu, Y.-K., Chen, J.-H., Chang, C. M. J., Liu, Y.-C. and Shieh, C.-J., “Continuous ultrasound-assisted packed-bed bioreactor for the lipase-catalyzed synthesis of caffeic acid phenethyl ester”, J. Chem. Tech. Biotech., 86, 1289-1294. (2011) (SCI, 1.818, Chem. Eng., 37/135=0. 27)
  68. Chen, H.-B., Wu, J.-Y., Wang, C.-F., Fu, C.-C., Shieh, C.-J., Chen, C.-I, Wang, C.-Y. and Liu, Y.-C.*, “Modeling on chlorophyll a and phycocyanin production by Spirulina platensis under various light-emitting diodes”, Biochem. Eng. J., 53, 52-56 (2010) (SCI, 2.692, Chem. Eng. , 16/135=0.12)
  69. Chen, H.-C., Twu, Y.-K., Chang, C. J., Liu, Y.-C., Shieh, C.-J., “Optimized synthesis of lipase-catalyzed octyl caffeate by Novozym 435”, Ind. Crop. Prod., 32, 522-526 (2010) (SCI, 2.507, Agri. Eng., 3/12=0.30)
  70. Lee, C.-C., Chen, H.-C., Ju, H.-Y., Liu, Y.-C., Chen, J.-H., Shie, S.-Y., Chang, C., and Shieh, C.-J., “Optimization of ultrasound-accelerated synthesis of enzymatic octyl hydroxyphenylpropionate by response surface methodology”, Biotechnol. Prog., 26, 1629-1634 (2010) (SCI, 2.178, Food Sci. Technol., 26/128=0.20)
  71. Chen, C.-I, Hwang, C.-C., Huang, C.-T., Tseng, H.-C., Chen, H.-B. and Liu, Y.-C.*, “Application of nano-carbon black immuno-Chromatographic test (NCBICT) on human serum albumin”, J. Biotech., 150S, S455 (2010) (SCI)
  72. Chen, H.-B., Chen, M.-J., Chen, C.-I, Huang, H.-C. and Liu, Y.-C.*, “Effect of using whey in the submerged culture of Grifola umbellata”, J. Biotech., 150S, S519 (2010) (SCI)
  73. Chen, H.-B., Huang, H.-C., Chen, C.-I, I, Y.-P. and Liu, Y.-C.*, “The use of additives as the stimulator on mycelial biomass and exopolysaccharide productions in submerged culture of Grifola umbellata”, Bioprocess Biosys. Eng., 33, 401-406 (2010) (SCI)
  74. Chen, H.-B., Kao, P.-M., Huang, H.-C., Shieh, C.-J., Chen, C.-I. and Liu, Y.-C.*, “Effects of using various bioreactors on chitinolytic enzymes production by Paenibacillus taichungensis”, Biochem. Eng. J., 49, 337-342 (2010) (SCI, 2.692, Chem. Eng. , 16/135=0.12)
  75. Ju, H.-Y., Huang, K.-C., Chen, J.-H., Liu, Y.-C., Chang, C.-M. J., Lee, C.-C., Chang, C., Shieh, C.-J., “Optimization of the Extraction of Alpinia oxyphylla Essence Oil in Supercritical Carbon Dioxide”, J. Am. Oil Chem. Soc., 87, 1063-1070 (2010) (SCI, 1.587, Food Sci. Technol., 43/128=0.34 )
  76. Ke, Y.-M., Chen, C.-I, Kao, P.-M., Chen, H.-B., Huang, H.-C., Yao, C.-J. and Liu, Y.-C.*, “Preparation of the immobilized metal affinity membrane with high amount of metal ions and protein adsorption efficiencies”, Proc. Biochem., 45, 500-506 (2010) (SCI, 2.648, Chem. Eng., 17/135=0.13)
  77. Chen, H.-C., Ju, H.-Y., Twu, Y.-K., Chen, J.-H., Chang, C.-M. J., Liu, Y.-C., Chang, C. and Shieh, C.-J., “Optimized enzymatic synthesis of caffeic acid phenethyl ester by RSM”, New Biotechnol., 27, 89-93 (2010) (SCI, 1.842, Biotechnol. & Appl. Microbiol.,82/160=0.51 )
  78. Kao, P.-M., Chen, C.-I., Huang, S.-C., Lin, K.-M., Chang, Y.-C. and Liu, Y.-C.*, “Preparation of Fermentation-Processed Chitin and Its Application in Chitinase Affinity Adsorption”, Proc. Biochem., 44, 343-348 (2009) (SCI, 2.648, Chem. Eng., 17/135=0.13)
  79. Huang, H.-C., Chen, C.-I., Hung, C.-N. and Liu, Y.-C.*, “Experimental Analysis of the Oil Addition Effect on Mycelia and Polysaccharide Productions in Ganoderma lucidum Submerged Culture”, Bioproc. Biosyst. Eng., 32, 217-224 (2009) (SCI, 2.060, Chem. Eng., 31/135=0.23)
  80. Wang, S.-J., Chang, W.-F., Wang, M.-Y., Hsiung, K.-P. and Liu, Y.-C.*, ” Development of a Disperse Dye Immunochromatographic Test for the Detection of Antibodies Against Infectious Bursal Disease Virus”, Vet. Immunol. Immunop.,125, 284-290 (2008) (SCI, 2.176, Vet. Sci., 13/145=0.09)
  81. Lee, F.-L., Tien, C.-J., Tai, C.-J., Wang, L.-T., Liu, Y.-C. And Chern, L.-L., “Paenibacillus taichungensis sp. nov., from Soil in Taiwan”, Int. J. Syst. Evol. Microbiol., 58, 2640–2645 (2008) (SCI, 1.930, Microbiol., 68/107=0.64)
  82. Huang, H.-C. and Liu, Y.-C.*, “Enhancement of polysaccharide production by optimization of culture conditions in shake flask submerged cultivation of Grifola umbellata”, J. Chin. Inst. Chem. Engrs., 39, 307-311 (2008) (SCI, 1.488, Chem. Eng., 47/135=0.35)
  83. Chen, C.-I, Kao, P.-M., Yao, C.-J. and Liu, Y.-C.*, “Development of an immobilized metal affinity membrane for penicillin g acylase purification”, J. Biotech., 136S, S505 (2008) (SCI)
  84. Wang, S.-J., Chang, W.-F., Chen, C.-I, Hsu, F.-S., Hsiung, K.-P. and Liu, Y.-C.*, “Application of nano-carbon black to immunochromatographic test”, J. Biotech., 136S, S193 (2008) (SCI)
  85. Chang, C.-H. and Liu, Y.-C.*, “Evaluation on Antioxidative Performance of Tomato Extracts Obtained by Different Methods”, J. Sci. Food Agri., 88, 612-618 (2008) (SCI, 1.360, Agriculture, 9/55=0.16)
  86. Chang, C.-H., Yu, T.-H., Chang, C.-Y. and Liu, Y.-C., “Impacts of Extraction Methods on Volatile Constituents of Longan Flower”, J. Food Drug Anal., 16, 46-52 (2008) (SCI, 0.615, Food Sci. Technol., 83/128=0.65)
  87. Wu, J.-Y., Lin, W.-C., Liu, Y.-C.*, Huang, J.-W. and Shih, H.-D., “Optimization of Cultivation Conditions for Fungichromin Production from Streptomyces padanus PMS-702", J. Chin. Inst. Chem. Engrs., 39, 67-73 (2008) (SCI, 1.488, Chem. Eng., 47/135=0.35)
  88. Chang, C.-H. and Liu, Y.-C.*, “Study on Lycopene and Antioxidant Contents Variations in Tomatoes under Air-drying Process”, J. Food Sci., 72, E532-540 (2007) (SCI, 1.733, Food Sci. Technol., 35/128=0.27)
  89. Huang, H.-C. and Liu, Y.-C.*, “Acceleration of Mycelia Growth by Adding Grifola umbellata Broth Concentrate in Solid-state and Submerged Cultures”, Biochem. Eng. J., 37, 139-143 (2007) (SCI, 2.692, Chem. Eng. , 16/135=0.12)
  90. Wang, C.-Y., Fu, C.-C., Liu, Y.-C. *, “Effects of Using Light-emitting Diodes on the Cultivation of Spirulina platensis”, Biochem. Eng. J., 37, 21-25 (2007) (SCI, 2.692, Chem. Eng. , 16/135=0.12)
  91. Chen, C.-I, Chen, C.-W., Huang, C.-W. and Liu, Y.-C.*, “Simultaneous Purification and Immobilization of Penicillin G Acylase Using Bifunctional Membrane”, J. Memb. Sci., 298, 24-29 (2007) (SCI, 3.673, Chem. Eng. , 8/135=0.06)
  92. Kao, P.-M., Huang, S.-C., Chang, Y.-C. and Liu, Y.-C.*, "Development of continuous chitinase production process in a membrane bioreactor by Paenibacillus sp. CHE-N1" Proc. Biochem., 42, 606-611 (2007) (SCI, 2.648, Chem. Eng., 17/135=0.13)
  93. Kao, P.-M., Chen, C.-I, Huang, S.-C., Chang, Y.-C., Tsai, P.-J. and Liu, Y.-C.*, "Effects of Shear Stress and Mass Transfer on Chitinase Production by Paenibacillus sp. CHE-N1", Biochem. Eng. J., 34, 172-178 (2007) (SCI, 2.692, Chem. Eng. , 16/135=0.12)
  94. Wang, S.-J., Lin, H.-M., Wang, X.-R., Hsiung, K.-P. and Liu, Y.-C.*, ”Optimized Dyeing Conditions of Immunoprotein with Reactive Dye Procion Blue MX-7RX”, Anal. Biochem., 361, 190-196 (2007) (SCI, 3.236, Anal. Chem., 16/73=0.22)
  95. Chang, C.-H., Lin, H.-Y., Chang, C.-Y. and Liu, Y.-C.*, “Comparisons on the Antioxidant Properties of Fresh, Freeze-Dried and hot-Air-Dried Tomatoes”, J. Food Eng., 77, 478-485 (2006) (SCI, 2.168, Chem. Eng., 26/135=0.19)
  96. Kao, P.-M., Tsai, P.-J., Liu, Y.-C.*, and Chang, Y.-C. “Optimization of Cultivation Conditions for the Production of Chitinase from Paenibacillus sp. CHE-N1”, J. Chin. Inst. Chem. Engrs., 37, 355-363 (2006) (SCI, 1.488, Chem. Eng., 47/135=0.35)
  97. Liu, Y.-C.*, Huang, G.. S., Wu, M.-C., Hong, M.-Y. and Hsiung, K.-P., “Detection of Foot and Mouth Disease and Porcine Reproductive Syndrome Viral Genes Using Microarray Chip”, Vet. Res. Commun., 30, 191-204 (2006) (SCI, 0.978, Vet. Sci., 61/145=0.42)
  98. Huang, H.-C., Lai, S.-F., Liu, Y.-C., Chen, H.-Y., Tu, W.-C., “Determination of Bromide Ion Residues in Broccoli after Fumigation with Methyl Bromide by Non-suppressed Ion-chromatography”, J. AOAC Int., 88, 1784-1787 (2005)  (SCI, 1.229, Food Sci. Technol., 53/128=0.41)
  99. Liu, Y.-C.*, Suen, S.-Y., Huang, C.-W. and ChangChien, C.-C., “Effects of Spacer Arm on Penicillin G Acylase Purification Using Immobilized Metal Affinity Membranes”, J. Memb. Sci., 251, 201-207 (2005) (SCI, 3.673, Chem. Eng. , 8/135=0.06)
  100. I, Y.-P., Liu, Y.-C., Han, K.-Y. and She, T.-C., “Construction of a Low-Pressure Microwave Plasma Reactor and Its Application in the Treatment of Volatile Organic Compounds”, Environ. Sci. Technol., 38, 3785-3791 (2004) (SCI, 4.827, Environ. Eng., 2/45=0.04)
  101. Liu, Y.-C.*, ChangChien, C.-C. and Suen, S.-Y., "Purification of Penicillin G Acylase Using Immobilized Metal Affinity Membranes", J. Chromatogr. B, 794, 67-76 (2003) (SCI, 2.971, Anal. Chem., 17/73=0.23)
  102. Suen, S.-Y., Liu, Y.-C. and Chang, C.-S., "Exploiting Immobilized Metal Affinity Membranes for the Isolation or Purification of Therapeutically Relevant Species", J. Chromatogr. B, 797, 305-319 (2003) (SCI, 2.971, Anal. Chem., 17/73=0.23)
  103. Liu, Y.-C.*, Wang, C.-M., Hsiung, K.-P. and Huang, C., "Evaluation and Application of Polymer Entrapment on Quartz Crystal Microbalance in Flow Injection Immunoassay", Biosen. Bioelectron., 18, 937-942 (2003) (SCI, 5.361, Electrochem., 1/26=0.04)
  104. Shih, H.-D., Liu, Y.-C., Hsu, F.-L., Mulabagal, V., Dodda, R. and Huang, J.-W., “Fungichromin: A Substance from Streptomyces padanus with Inhibitory Effects on Rhizoctonia solani”, J. Agri. Food Chem., 51, 95-99 (2003) (SCI, 2.816, Agriculture, 2/55=0.04)
  105. Huang, G. S., Hong, M.Y. and Liu, Y.-C., “Incorporation of DNA Chip Technology to the Simulation and Validation of Flux Analysis in Yeast Diauxic Growth”, Life Sci., 72, 2525-2531 (2003) (SCI, 2.451, Pharmacol. Pharmacy  , 115/252=0.46)
  106. Liu, Y.-C.*, Wang, C.-M. and Hsiung, K.-P., ”Comparison of Different Protein Immobilization Methods on Quartz Crystal Microbalance Surface in Flow Injection Immunoassay”, Anal. Biochem., 299, 130-135 (2001) (SCI, 3.236, Anal. Chem., 16/73=0.22)
  107. Liu, Y.-C.*, Cheng, K.-Y., Huang, G. S., ”Singularity Analysis on the Metabolic Network Equations”, J. Chin. Inst. Chem. Engrs., 32, 69-73 (2001) (SCI, 1.488, Chem. Eng., 47/135=0.35)
  108. Liu, Y.-C.*, Chang, H. and I, Y.-P., “A Neural Network Model for Estimating Oxygen Absorption Coefficient in Shake-Flasks”, Biotechnol. Lett., 22, 1885-1888 (2000) (SCI, 1.768, Biotechnol. & Appl. Microbiol., 86/160=0.54)
  109. Liu, Y.-C.* and K.-Y. Cheng, “Effect of Ammonium Concentration on the Cultivation of Recombinant E. coli Producing Penicillin G Acylase”, J. Chin. Inst. Chem. Engrs., 31, 601-607 (2000) (SCI, 1.488, Chem. Eng., 47/135=0.35)
  110. Huang, G. S., Yang, S.-M., Hong, M.-Y., Yang, P.-C. and Liu, Y.-C., “Differential Gene Expression of Livers from ApoE Deficient Mice”, Life Sci., 68, 19-28 (2000) (SCI, 2.451, Pharmacol. Pharmacy  , 115/252=0.46)
  111. Liu, Y.-C.*, Liao, L.-C. and Wu, W.-T., “Cultivation of recombinant E. coli to achieve high cell density with a high level of penicillin G acylase activity”, Proc. Natl. Sci. Counc. ROC(B), 24, 156-160 (2000) EI
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著作權及專利

  1. 劉永銓,“北蟲草多批次生產發酵生產胞外多醣體的方法”, 中華民國專利 I693285號 (2020)
  2. 王建章,余世宗,劉永銓,張景煇,張仁聰,“電極殺菌裝置”, 中華民國新型專利M565199號 (2018)
  3. 張景煇,陳玟吟,劉永銓,林家騏,“檢測哈威式弧菌之探針”, 中華民國專利I 539003B號 (2016)
  4. 黃振文,彭玉湘,劉永銓,鄭政峯,鄭倩芸,“具有防治瓜類蔬菜幼苗猝倒病與十字花科根瘤病的蕈狀芽孢桿菌新菌系”, 中華民國專利I 510619號 (2015)
  5. 劉永銓,黃振文,鄭政峯,姚文法,彭玉香,許爵軒, “葷狀芽抱桿菌共培養物及其於生產界面活性劑之應用”, 中華民國專利I 486444號 (2015)
  6. Liu, Y.-C., Wu, J.-Y., Lin, C.-C., “Expression cassette, recombinant host cell and process for producing a target protein”, US patent 8759028B2 (2014)
  7. 劉永銓,吳俊彥, “用於生產一標的蛋白質的核酸建構物、重組型載體以及方法”, 中華民國專利I 408228號 (2013)
  8. 劉永銓,陳華彬, “利用菇類回收廢棄菌包為材料之酵素萃取方法”, 中華民國專利I 392535號 (2013)
  9. 劉永銓,陳志義, “固定化金屬親和薄膜及其製備方法、由其製得之金屬錯合膜以及固定化酵素膜”, 中華民國專利I 382045號 (2013)
  10. 劉永銓,陳志義, “經固定酵素的固定化金屬親和薄膜之再生製備方法”, 中華民國專利I 368652號 (2012)
  11. 劉永銓,黃振文,林鎧民, “生產改質幾丁質之方法及應用該改質幾丁質純化幾丁酵素之方法”, 中華民國專利I 344992號 (2011)
  12. 劉永銓,黃振文,羅淇文,石信德, “生產治黴色基素之方法”, 中華民國專利I 338048號 (2011)
  13. 姚文法,劉永銓,王智民,羅士泱,賴傑宏,熊光濱,“機動型掃瞄式檢驗分析儀”, 中華民國專利I 245899號(2005)
  14. 王智民,劉永銓,姚文法,熊光濱,“生物感測器之流體檢驗室裝置及其應用”, 中華民國專利I 207040號(2004)
  15. 黃振文,石信德,劉永銓,徐鳳麟, “植物保護用鏈黴菌(Streptomyces padanus PMS-702)組成物製劑及其製法”, 中華民國專利I 224142號(2004)
  16. 姚文法,劉永銓,羅士泱, “回饋式自動控制冷凍乾燥之裝置”, 中華民國新型專利139561號(1998)
  17. 朱燕華,劉永銓, “米糠中肌醇回收率改善之方法”, 中華民國新型專利43630號(1990)
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